Identification of modulators of autophagic flux in an image-based high content siRNA screen

Autophagy is the primary process for recycling cellular constituents through lysosomal degradation. In addition to nonselective autophagic engulfment of cytoplasm, autophagosomes can recognize specific cargo by interacting with ubiquitin-binding autophagy receptors such as SQSTM1/p62 (sequestosome 1...

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Опубликовано в: :Autophagy
Главные авторы: Hale, Christopher M., Cheng, Qingwen, Ortuno, Danny, Huang, Ming, Nojima, Dana, Kassner, Paul D., Wang, Songli, Ollmann, Michael M., Carlisle, Holly J.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836002/
https://ncbi.nlm.nih.gov/pubmed/27050463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1147669
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