Identification of modulators of autophagic flux in an image-based high content siRNA screen

Autophagy is the primary process for recycling cellular constituents through lysosomal degradation. In addition to nonselective autophagic engulfment of cytoplasm, autophagosomes can recognize specific cargo by interacting with ubiquitin-binding autophagy receptors such as SQSTM1/p62 (sequestosome 1...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Hale, Christopher M., Cheng, Qingwen, Ortuno, Danny, Huang, Ming, Nojima, Dana, Kassner, Paul D., Wang, Songli, Ollmann, Michael M., Carlisle, Holly J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836002/
https://ncbi.nlm.nih.gov/pubmed/27050463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1147669
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