Identification of modulators of autophagic flux in an image-based high content siRNA screen

Autophagy is the primary process for recycling cellular constituents through lysosomal degradation. In addition to nonselective autophagic engulfment of cytoplasm, autophagosomes can recognize specific cargo by interacting with ubiquitin-binding autophagy receptors such as SQSTM1/p62 (sequestosome 1...

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Publié dans:Autophagy
Auteurs principaux: Hale, Christopher M., Cheng, Qingwen, Ortuno, Danny, Huang, Ming, Nojima, Dana, Kassner, Paul D., Wang, Songli, Ollmann, Michael M., Carlisle, Holly J.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836002/
https://ncbi.nlm.nih.gov/pubmed/27050463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1147669
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