Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

The antimitotic anti-cancer drugs, including taxol, perturb spindle dynamics, and induce prolonged, spindle checkpoint-dependent mitotic arrest in cancer cells. These cells then either undergo apoptosis triggered by the intrinsic mitochondrial pathway or exit mitosis without proper cell division in...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Díaz-Martínez, Laura A, Karamysheva, Zemfira N, Warrington, Ross, Li, Bing, Wei, Shuguang, Xie, Xian-Jin, Roth, Michael G, Yu, Hongtao
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Resource
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195789/
https://ncbi.nlm.nih.gov/pubmed/25024437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201487826
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky