The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14

ULK1 (unc-51 like autophagy activating kinase 1), the key mediator of MTORC1 signaling to autophagy, regulates early stages of autophagosome formation in response to starvation or MTORC1 inhibition. How ULK1 regulates the autophagy induction process remains elusive. Here, we identify that ATG13, a b...

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Bibliografski detalji
Izdano u:Autophagy
Glavni autori: Park, Ji-Man, Jung, Chang Hwa, Seo, Minchul, Otto, Neil Michael, Grunwald, Douglas, Kim, Kwan Hyun, Moriarity, Branden, Kim, Young-Mi, Starker, Colby, Nho, Richard Seonghun, Voytas, Daniel, Kim, Do-Hyung
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Basic Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835982/
https://ncbi.nlm.nih.gov/pubmed/27046250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1140293
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