BNIP3 is degraded by ULK1-dependent autophagy via MTORC1 and AMPK

BNIP3 (BCL2/adenovirus E1B 19 kDa interacting protein 3) is an atypical BH3-only protein that is induced by hypoxia-inducible factor 1 (HIF1) under hypoxia. BNIP3 is primarily regulated at the transcriptional level. However, little is known about the underlying mechanism of BNIP3 degradation. In thi...

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Bibliografiska uppgifter
Huvudupphovsmän: Park, Chang Wook, Hong, Sun Mi, Kim, Eung-Sam, Kwon, Jung Hee, Kim, Kyong-Tai, Nam, Hong Gil, Choi, Kwan Yong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2013
Ämnen:
Basic Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590255/
https://ncbi.nlm.nih.gov/pubmed/23291726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23072
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