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BNIP3 is degraded by ULK1-dependent autophagy via MTORC1 and AMPK
BNIP3 (BCL2/adenovirus E1B 19 kDa interacting protein 3) is an atypical BH3-only protein that is induced by hypoxia-inducible factor 1 (HIF1) under hypoxia. BNIP3 is primarily regulated at the transcriptional level. However, little is known about the underlying mechanism of BNIP3 degradation. In thi...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590255/ https://ncbi.nlm.nih.gov/pubmed/23291726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23072 |
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