Quantifying the effect of Vpu on the promotion of HIV-1 replication in the humanized mouse model

BACKGROUND: Tetherin is an intrinsic anti-viral factor impairing the release of nascent HIV-1 particles from infected cells. Vpu, an HIV-1 accessory protein, antagonizes the anti-viral action of tetherin. Although previous studies using in vitro cell culture systems have revealed the molecular mecha...

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Bibliografiske detaljer
Udgivet i:Retrovirology
Main Authors: Ikeda, Hiroki, Nakaoka, Shinji, de Boer, Rob J., Morita, Satoru, Misawa, Naoko, Koyanagi, Yoshio, Aihara, Kazuyuki, Sato, Kei, Iwami, Shingo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834825/
https://ncbi.nlm.nih.gov/pubmed/27086687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0252-2
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