Improving the estimation of the death rate of infected cells from time course data during the acute phase of virus infections: application to acute HIV-1 infection in a humanized mouse model

BACKGROUND: Mathematical modeling of virus dynamics has provided quantitative insights into viral infections such as influenza, the simian immunodeficiency virus/human immunodeficiency virus, hepatitis B, and hepatitis C. Through modeling, we can estimate the half-life of infected cells, the exponen...

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Detalhes bibliográficos
Main Authors: Ikeda, Hiroki, de Boer, Rob J, Sato, Kei, Morita, Satoru, Misawa, Naoko, Koyanagi, Yoshio, Aihara, Kazuyuki, Iwami, Shingo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035760/
https://ncbi.nlm.nih.gov/pubmed/24885827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-11-22
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