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HIV-1 Vpr Accelerates Viral Replication during Acute Infection by Exploitation of Proliferating CD4(+) T Cells In Vivo
The precise role of viral protein R (Vpr), an HIV-1-encoded protein, during HIV-1 infection and its contribution to the development of AIDS remain unclear. Previous reports have shown that Vpr has the ability to cause G(2) cell cycle arrest and apoptosis in HIV-1-infected cells in vitro. In addition...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855622/ https://ncbi.nlm.nih.gov/pubmed/24339781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003812 |
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