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Vpu Augments the Initial Burst Phase of HIV-1 Propagation and Downregulates BST2 and CD4 in Humanized Mice

While human cells express potent antiviral proteins as part of the host defense repertoire, viruses have evolved their own arsenal of proteins to antagonize them. BST2 was identified as an inhibitory cellular protein of HIV-1 replication, which tethers virions to the cell surface to prevent their re...

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Detalhes bibliográficos
Main Authors: Sato, Kei, Misawa, Naoko, Fukuhara, Mitsuko, Iwami, Shingo, An, Dong Sung, Ito, Mamoru, Koyanagi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347374/
https://ncbi.nlm.nih.gov/pubmed/22357275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07062-11
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