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Optimization of 2-Phenylcyclopropylmethylamines as Selective Serotonin 2C Receptor Agonists and Their Evaluation as Potential Antipsychotic Agents
The discovery of a new series of compounds that are potent, selective 5-HT(2C) receptor agonists is described herein as we continue our efforts to optimize the 2-phenylcyclopropylmethylamine scaffold. Modifications focused on the alkoxyl substituent present on the aromatic ring led to the identifica...
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發表在: | J Med Chem |
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Main Authors: | , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834193/ https://ncbi.nlm.nih.gov/pubmed/25633969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5019274 |
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