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Experimental inhibition of porcupine mediated Wnt O-acylation attenuates kidney fibrosis
Activated Wnt signaling is critical in the pathogenesis of renal fibrosis, a final common pathway for most forms of chronic kidney disease. Therapeutic intervention by inhibition of individual Wnts or downstream Wnt/β-catenin signaling has been proposed, but these approaches do not interrupt the fun...
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| Publicado no: | Kidney Int |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834146/ https://ncbi.nlm.nih.gov/pubmed/27083283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.01.017 |
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