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Bacterial Riboswitches and Ribozymes Potently Activate the Human Innate Immune Sensor PKR
The innate immune system provides the first line of defense against pathogens through the recognition of non-specific patterns in RNA to protect the cell in a generalized way. The human RNA-activated protein kinase, PKR, is a dsRNA binding protein and an essential sensor in the innate immune respons...
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| Published in: | ACS Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833549/ https://ncbi.nlm.nih.gov/pubmed/27011290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00081 |
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