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ERRγ is required for the metabolic maturation of therapeutically functional glucose-responsive β cells
Pancreatic β cells undergo postnatal maturation to achieve maximal glucose-responsive insulin secretion, an energy intensive process. We identify estrogen-related receptor γ (ERRγ) expression as a hallmark of adult, but not neonatal β cells. Postnatal induction of ERRγ drives a transcriptional netwo...
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| Publicat a: | Cell Metab |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832237/ https://ncbi.nlm.nih.gov/pubmed/27076077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.03.005 |
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