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PPARγ signaling and metabolism: the good, the bad and the future
Thiazolidinediones (TZDs) are potent insulin sensitizers that act through the nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) and are highly effective oral medications for type 2 diabetes. However, their unique benefits are shadowed by the risk for fluid retention, weight gain,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870016/ https://ncbi.nlm.nih.gov/pubmed/23652116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3159 |
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