PPARγ signaling and metabolism: the good, the bad and the future

Thiazolidinediones (TZDs) are potent insulin sensitizers that act through the nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) and are highly effective oral medications for type 2 diabetes. However, their unique benefits are shadowed by the risk for fluid retention, weight gain,...

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Bibliografiske detaljer
Main Authors: Ahmadian, Maryam, Suh, Jae Myoung, Hah, Nasun, Liddle, Christopher, Atkins, Annette R, Downes, Michael, Evans, Ronald M
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870016/
https://ncbi.nlm.nih.gov/pubmed/23652116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3159
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