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ERRγ promotes angiogenesis, mitochondrial biogenesis and oxidative remodeling in PGC1α/β-deficient muscle

PGC1α is a pleiotropic co-factor that affects angiogenesis, mitochondrial biogenesis and oxidative muscle remodeling via its association with multiple transcription factors including the master oxidative nuclear receptor ERRγ. To decipher their epistatic relationship, we explored ERRγ gain-of-functi...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Fan, Weiwei, He, Nanhai, Lin, Chun Shi, Wei, Zong, Hah, Nasun, Waizenegger, Wanda, He, Ming-Xiao, Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860878/
https://ncbi.nlm.nih.gov/pubmed/29514081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.047
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