ERRγ promotes angiogenesis, mitochondrial biogenesis and oxidative remodeling in PGC1α/β-deficient muscle

PGC1α is a pleiotropic co-factor that affects angiogenesis, mitochondrial biogenesis and oxidative muscle remodeling via its association with multiple transcription factors including the master oxidative nuclear receptor ERRγ. To decipher their epistatic relationship, we explored ERRγ gain-of-functi...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Fan, Weiwei, He, Nanhai, Lin, Chun Shi, Wei, Zong, Hah, Nasun, Waizenegger, Wanda, He, Ming-Xiao, Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860878/
https://ncbi.nlm.nih.gov/pubmed/29514081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.047
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