ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency

Cell metabolism is adaptive to extrinsic demands, however the intrinsic metabolic demands that drive the induced pluripotent stem cell (iPSC) program remain unclear. While glycolysis increases throughout the reprogramming process, we show that the estrogen related nuclear receptors (ERRα and γ) and...

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Vydáno v:Cell Stem Cell
Hlavní autoři: Kida, Yasuyuki S., Kawamura, Teruhisa, Wei, Zong, Sogo, Takahiro, Jacinto, Sandra, Shigeno-Kamitsuji, Asako, Yoshihara, Eiji, Liddle, Christopher, Ecker, Joseph R., Yu, Ruth T., Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427539/
https://ncbi.nlm.nih.gov/pubmed/25865501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.03.001
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