ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency

Cell metabolism is adaptive to extrinsic demands, however the intrinsic metabolic demands that drive the induced pluripotent stem cell (iPSC) program remain unclear. While glycolysis increases throughout the reprogramming process, we show that the estrogen related nuclear receptors (ERRα and γ) and...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Kida, Yasuyuki S., Kawamura, Teruhisa, Wei, Zong, Sogo, Takahiro, Jacinto, Sandra, Shigeno-Kamitsuji, Asako, Yoshihara, Eiji, Liddle, Christopher, Ecker, Joseph R., Yu, Ruth T., Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427539/
https://ncbi.nlm.nih.gov/pubmed/25865501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.03.001
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