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ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency
Cell metabolism is adaptive to extrinsic demands, however the intrinsic metabolic demands that drive the induced pluripotent stem cell (iPSC) program remain unclear. While glycolysis increases throughout the reprogramming process, we show that the estrogen related nuclear receptors (ERRα and γ) and...
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| Publicado en: | Cell Stem Cell |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4427539/ https://ncbi.nlm.nih.gov/pubmed/25865501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.03.001 |
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