ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency

Cell metabolism is adaptive to extrinsic demands, however the intrinsic metabolic demands that drive the induced pluripotent stem cell (iPSC) program remain unclear. While glycolysis increases throughout the reprogramming process, we show that the estrogen related nuclear receptors (ERRα and γ) and...

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Bibliografiska uppgifter
I publikationen:Cell Stem Cell
Huvudupphovsmän: Kida, Yasuyuki S., Kawamura, Teruhisa, Wei, Zong, Sogo, Takahiro, Jacinto, Sandra, Shigeno-Kamitsuji, Asako, Yoshihara, Eiji, Liddle, Christopher, Ecker, Joseph R., Yu, Ruth T., Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427539/
https://ncbi.nlm.nih.gov/pubmed/25865501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.03.001
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