Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally

Somatic cell nuclear transfer has established that the oocyte contains maternal factors with epigenetic reprogramming capacity. Yet the identity and function of these maternal factors during the gamete to embryo transition remains poorly understood. In C. elegans, LSD1/KDM1A enables this transition...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Wasson, Jadiel A, Simon, Ashley K, Myrick, Dexter A, Wolf, Gernot, Driscoll, Shawn, Pfaff, Samuel L, Macfarlan, Todd S, Katz, David J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Developmental Biology and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829428/
https://ncbi.nlm.nih.gov/pubmed/26814574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08848
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