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Bivalent compound 17MN exerts neuroprotection through interaction at multiple sites in a cellular model of Alzheimer’s disease

Multiple pathogenic factors have been suggested in playing a role in the development of Alzheimer’s disease (AD). The multifactorial nature of AD also suggests the potential use of compounds with polypharmacology as effective disease-modifying agents. Recently, we have developed a bivalent strategy...

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Dettagli Bibliografici
Pubblicato in:J Alzheimers Dis
Autori principali: Liu, Kai, Chojnacki, Jeremy E., Wade, Emily E., Saathoff, John M., Lesnefsky, Edward J., Chen, Qun, Zhang, Shijun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829378/
https://ncbi.nlm.nih.gov/pubmed/26401780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150242
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