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Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer’s disease
In an effort to combat the multifaceted nature of Alzheimer’s disease (AD) progression, a series of multifunctional, bivalent compounds containing curcumin and diosgenin were designed, synthesized, and biologically characterized. Screening results in MC65 neuroblastoma cells established that compoun...
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Publicat a: | Bioorg Med Chem |
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Autors principals: | , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641451/ https://ncbi.nlm.nih.gov/pubmed/26526742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.10.032 |
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