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Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer’s disease

In an effort to combat the multifaceted nature of Alzheimer’s disease (AD) progression, a series of multifunctional, bivalent compounds containing curcumin and diosgenin were designed, synthesized, and biologically characterized. Screening results in MC65 neuroblastoma cells established that compoun...

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Библиографические подробности
Опубликовано в: :Bioorg Med Chem
Главные авторы: Chojnacki, Jeremy E., Liu, Kai, Saathoff, John M., Zhang, Shijun
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641451/
https://ncbi.nlm.nih.gov/pubmed/26526742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.10.032
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