Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer’s disease

Por Chojnacki, Jeremy E., Liu, Kai, Saathoff, John M., Zhang, Shijun
Publicado no Bioorg Med Chem (2015)

Mechanistic Insight of Bivalent Compound 21MO as Potential Neuroprotectant for Alzheimer’s Disease

Por Saathoff, John M., Liu, Kai, Chojnacki, Jeremy E., He, Liu, Chen, Qun, Lesnefsky, Edward J., Zhang, Shijun
Publicado no Molecules (2016)

Bivalent compound 17MN exerts neuroprotection through interaction at multiple sites in a cellular model of Alzheimer’s disease

Por Liu, Kai, Chojnacki, Jeremy E., Wade, Emily E., Saathoff, John M., Lesnefsky, Edward J., Chen, Qun, Zhang, Shijun
Publicado no J Alzheimers Dis (2015)

A curcumin/melatonin hybrid, 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide, ameliorates AD-like pathology in the APP/PS1 mouse model

Por Gerenu, Gorka, Liu, Kai, Chojnacki, Jeremy E., Saathoff, John M., Martínez-Martín, Pablo, Perry, George, Zhu, Xiongwei, Lee, Hyoung-gon, Zhang, Shijun
Publicado no ACS Chem Neurosci (2015)