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Development of bivalent compounds as potential neuroprotectants for Alzheimer’s disease

In our efforts to further investigate the impact of the spacer and membrane anchor to the neuroprotective activities, a series of bivalent compounds that contain cholesterol and extended spacers were designed, synthesized and biologically characterized. Our results support previous studies that inco...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: He, Liu, Jiang, Yuqi, Green, Jakob, Blevins, Hallie, Zhang, Shijun
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938236/
https://ncbi.nlm.nih.gov/pubmed/31153803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.05.035
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