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Development of bivalent compounds as potential neuroprotectants for Alzheimer’s disease
In our efforts to further investigate the impact of the spacer and membrane anchor to the neuroprotective activities, a series of bivalent compounds that contain cholesterol and extended spacers were designed, synthesized and biologically characterized. Our results support previous studies that inco...
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| Опубликовано в: : | Bioorg Med Chem Lett |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6938236/ https://ncbi.nlm.nih.gov/pubmed/31153803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.05.035 |
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