Llwytho...

Design and characterization of bivalent compounds as potential neuroprotectants for Alzheimer’s disease: Impact of the spacer on biological activity

In our continuing efforts to develop bivalent compounds as potential neuroprotectants for Alzheimer’s disease, a series of bivalent compounds that contain cholesterylamine and an extended spacer were synthesized and biologically characterized. Our results demonstrated that incorporation of a piperaz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Med Chem Lett
Prif Awduron: He, Liu, Boice, Ashley, Liu, Kai, Yan, Xing, Jiang, Yuqi, Zhang, Shijun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851865/
https://ncbi.nlm.nih.gov/pubmed/29475586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.02.028
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