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Quantitative evaluation of first, second, and third generation hairpin systems reveals the limit of mammalian vector-based RNAi
Incorporating miRNA-like features into vector-based hairpin scaffolds has been shown to augment small RNA processing and RNAi efficiency. Therefore, defining an optimal, native hairpin context may obviate a need for hairpin-specific targeting design schemes, which confound the movement of functional...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4829305/ https://ncbi.nlm.nih.gov/pubmed/26786363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1128062 |
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