Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine

ABSTRACT: Cytochrome P450 (CYP) 2S1 is “orphan” CYP that is overexpressed in several epithelial tissues and many human tumors. The pure enzyme is required for better understanding of its biological functions. Therefore, human CYP2S1 was considered to be prepared by the gene manipulations and heterol...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Monatsh Chem
मुख्य लेखकों: Mrízová, Iveta, Moserová, Michaela, Milichovský, Jan, Šulc, Miroslav, Kizek, René, Kubáčková, Kateřina, Arlt, Volker M., Stiborová, Marie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer Vienna 2016
विषय:
Original Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828499/
https://ncbi.nlm.nih.gov/pubmed/27110039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1738-2
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