Intracranial AAV‐sTRAIL combined with lanatoside C prolongs survival in an orthotopic xenograft mouse model of invasive glioblastoma

Glioblastoma (GBM) is the most common malignant brain tumor in adults. We designed an adeno‐associated virus (AAV) vector for intracranial delivery of secreted, soluble tumor necrosis factor‐related apoptosis‐inducing ligand (sTRAIL) to GBM tumors in mice and combined it with the TRAIL‐sensitizing c...

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Detaylı Bibliyografya
Yayımlandı:Mol Oncol
Asıl Yazarlar: Crommentuijn, Matheus H.W., Maguire, Casey A., Niers, Johanna M., Vandertop, W. Peter, Badr, Christian E., Würdinger, Thomas, Tannous, Bakhos A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826802/
https://ncbi.nlm.nih.gov/pubmed/26708508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.11.011
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