Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor–related apoptosis-inducing ligand and induces an alternative cell death pathway

Human glioblastoma (GBM) cells are notorious for their resistance to apoptosis-inducing therapeutics. We have identified lanatoside C as a sensitizer of GBM cells to tumor necrosis factor–related apoptosis-inducing ligand (TRAIL)–induced cell death partly by upregulation of the death receptor 5. We...

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Bibliographic Details
Main Authors: Badr, Christian E., Wurdinger, Thomas, Nilsson, Jonas, Niers, Johanna M., Whalen, Michael, Degterev, Alexei, Tannous, Bakhos A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199161/
https://ncbi.nlm.nih.gov/pubmed/21757445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor067
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