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Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo

Recently adeno-associated virus (AAV) became the first clinically approved gene therapy product in the western world. To develop AAV for future clinical application in a widespread patient base, particularly in therapies which require intravenous (i.v.) administration of vector, the virus must be ab...

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Detalhes bibliográficos
Main Authors: György, Bence, Fitzpatrick, Zachary, Crommentuijn, Matheus HW, Mu, Dakai, Maguire, Casey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104587/
https://ncbi.nlm.nih.gov/pubmed/24917028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.05.032
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