Microvesicle-associated AAV Vector as a Novel Gene Delivery System

Adeno-associated virus (AAV) vectors have shown remarkable efficiency for gene delivery to cultured cells and in animal models of human disease. However, limitations to AAV vectored gene transfer exist after intravenous transfer, including off-target gene delivery (e.g., liver) and low transduction...

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Detalhes bibliográficos
Main Authors: Maguire, Casey A, Balaj, Leonora, Sivaraman, Sarada, Crommentuijn, Matheus HW, Ericsson, Maria, Mincheva-Nilsson, Lucia, Baranov, Vladimir, Gianni, Davide, Tannous, Bakhos A, Sena-Esteves, Miguel, Breakefield, Xandra O, Skog, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345986/
https://ncbi.nlm.nih.gov/pubmed/22314290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.303
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