Microvesicle-associated AAV Vector as a Novel Gene Delivery System

Adeno-associated virus (AAV) vectors have shown remarkable efficiency for gene delivery to cultured cells and in animal models of human disease. However, limitations to AAV vectored gene transfer exist after intravenous transfer, including off-target gene delivery (e.g., liver) and low transduction...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Maguire, Casey A, Balaj, Leonora, Sivaraman, Sarada, Crommentuijn, Matheus HW, Ericsson, Maria, Mincheva-Nilsson, Lucia, Baranov, Vladimir, Gianni, Davide, Tannous, Bakhos A, Sena-Esteves, Miguel, Breakefield, Xandra O, Skog, Johan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345986/
https://ncbi.nlm.nih.gov/pubmed/22314290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.303
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge