Microvesicle-associated AAV Vector as a Novel Gene Delivery System

Adeno-associated virus (AAV) vectors have shown remarkable efficiency for gene delivery to cultured cells and in animal models of human disease. However, limitations to AAV vectored gene transfer exist after intravenous transfer, including off-target gene delivery (e.g., liver) and low transduction...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Maguire, Casey A, Balaj, Leonora, Sivaraman, Sarada, Crommentuijn, Matheus HW, Ericsson, Maria, Mincheva-Nilsson, Lucia, Baranov, Vladimir, Gianni, Davide, Tannous, Bakhos A, Sena-Esteves, Miguel, Breakefield, Xandra O, Skog, Johan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345986/
https://ncbi.nlm.nih.gov/pubmed/22314290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.303
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