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Strain Promoted Click Chemistry of 2- or 8-Azidopurine and 5-Azidopyrimidine Nucleosides and 8-Azidoadenosine Triphosphate with Cyclooctynes. Application to Living Cell Fluorescent Imaging

Strain-promoted click chemistry of nucleosides and nucleotides with an azido group directly attached to the purine and pyrimidine rings with various cyclooctynes in aqueous solution at ambient temperature resulted in efficient formation (3 min - 3 h) of fluorescent, light-up, triazole products. The...

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Détails bibliographiques
Publié dans:Bioconjug Chem
Auteurs principaux: Zayas, Jessica, Annoual, Marie, Das, Jayanta Kumar, Felty, Quentin, Gonzalez, Walter G., Miksovska, Jaroslava, Sharifai, Nima, Chiba, Akira, Wnuk, Stanislaw F.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826778/
https://ncbi.nlm.nih.gov/pubmed/26086070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00300
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