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Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistry
[Image: see text] Cyclooctyne-based probes that become fluorescent upon reaction with azides are important targets for real-time imaging of azide-labeled biomolecules. The concise synthesis of a coumarin-conjugated cyclooctyne, coumBARAC, that undergoes a 10-fold enhancement in fluorescence quantum...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219546/ https://ncbi.nlm.nih.gov/pubmed/22029411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2025026 |
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