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Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistry

[Image: see text] Cyclooctyne-based probes that become fluorescent upon reaction with azides are important targets for real-time imaging of azide-labeled biomolecules. The concise synthesis of a coumarin-conjugated cyclooctyne, coumBARAC, that undergoes a 10-fold enhancement in fluorescence quantum...

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Bibliografische gegevens
Hoofdauteurs: Jewett, John C., Bertozzi, Carolyn R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219546/
https://ncbi.nlm.nih.gov/pubmed/22029411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2025026
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