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Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry

[Image: see text] The 1,3-dipolar cycloaddition of cyclooctynes with azides, also called “copper-free click chemistry”, is a bioorthogonal reaction with widespread applications in biological discovery. The kinetics of this reaction are of paramount importance for studies of dynamic processes, partic...

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Hlavní autoři: Gordon, Chelsea G., Mackey, Joel L., Jewett, John C., Sletten, Ellen M., Houk, K. N., Bertozzi, Carolyn R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2012
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368396/
https://ncbi.nlm.nih.gov/pubmed/22553995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3000936
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