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Copper-free click chemistry in living animals

Chemical reactions that enable selective biomolecule labeling in living organisms offer a means to probe biological processes in vivo. Very few reactions possess the requisite bioorthogonality, and, among these, only the Staudinger ligation between azides and triarylphosphines has been employed for...

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Detalhes bibliográficos
Main Authors: Chang, Pamela V., Prescher, Jennifer A., Sletten, Ellen M., Baskin, Jeremy M., Miller, Isaac A., Agard, Nicholas J., Lo, Anderson, Bertozzi, Carolyn R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836626/
https://ncbi.nlm.nih.gov/pubmed/20080615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911116107
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