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Strain Promoted Click Chemistry of 2- or 8-Azidopurine and 5-Azidopyrimidine Nucleosides and 8-Azidoadenosine Triphosphate with Cyclooctynes. Application to Living Cell Fluorescent Imaging

Strain-promoted click chemistry of nucleosides and nucleotides with an azido group directly attached to the purine and pyrimidine rings with various cyclooctynes in aqueous solution at ambient temperature resulted in efficient formation (3 min - 3 h) of fluorescent, light-up, triazole products. The...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Zayas, Jessica, Annoual, Marie, Das, Jayanta Kumar, Felty, Quentin, Gonzalez, Walter G., Miksovska, Jaroslava, Sharifai, Nima, Chiba, Akira, Wnuk, Stanislaw F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826778/
https://ncbi.nlm.nih.gov/pubmed/26086070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00300
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