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G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells

DNA methylation at imprinting control regions (ICRs) is established in gametes in a sex-specific manner and has to be stably maintained during development and in somatic cells to ensure the correct monoallelic expression of imprinted genes. In addition to DNA methylation, the ICRs are marked by alle...

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Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Zhang, Tuo, Termanis, Ausma, Özkan, Burak, Bao, Xun X., Culley, Jayne, de Lima Alves, Flavia, Rappsilber, Juri, Ramsahoye, Bernard, Stancheva, Irina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826439/
https://ncbi.nlm.nih.gov/pubmed/27052169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.007
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