G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells

DNA methylation at imprinting control regions (ICRs) is established in gametes in a sex-specific manner and has to be stably maintained during development and in somatic cells to ensure the correct monoallelic expression of imprinted genes. In addition to DNA methylation, the ICRs are marked by alle...

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Publicat a:Cell Rep
Autors principals: Zhang, Tuo, Termanis, Ausma, Özkan, Burak, Bao, Xun X., Culley, Jayne, de Lima Alves, Flavia, Rappsilber, Juri, Ramsahoye, Bernard, Stancheva, Irina
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826439/
https://ncbi.nlm.nih.gov/pubmed/27052169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.007
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