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G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells

DNA methylation at imprinting control regions (ICRs) is established in gametes in a sex-specific manner and has to be stably maintained during development and in somatic cells to ensure the correct monoallelic expression of imprinted genes. In addition to DNA methylation, the ICRs are marked by alle...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Zhang, Tuo, Termanis, Ausma, Özkan, Burak, Bao, Xun X., Culley, Jayne, de Lima Alves, Flavia, Rappsilber, Juri, Ramsahoye, Bernard, Stancheva, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826439/
https://ncbi.nlm.nih.gov/pubmed/27052169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.007
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