G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells

DNA methylation at imprinting control regions (ICRs) is established in gametes in a sex-specific manner and has to be stably maintained during development and in somatic cells to ensure the correct monoallelic expression of imprinted genes. In addition to DNA methylation, the ICRs are marked by alle...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Zhang, Tuo, Termanis, Ausma, Özkan, Burak, Bao, Xun X., Culley, Jayne, de Lima Alves, Flavia, Rappsilber, Juri, Ramsahoye, Bernard, Stancheva, Irina
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826439/
https://ncbi.nlm.nih.gov/pubmed/27052169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.007
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