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The SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells

LSH, a protein related to the SNF2 family of chromatin-remodelling ATPases, is essential for the correct establishment of DNA methylation levels and patterns in plants and mammalian cells. However, some of the phenotypes resulting from LSH deficiency cannot be explained easily by defects in DNA meth...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Burrage, Joe, Termanis, Ausma, Geissner, Andreas, Myant, Kevin, Gordon, Katrina, Stancheva, Irina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Company of Biologists 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561860/
https://ncbi.nlm.nih.gov/pubmed/22946062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.111252
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