Dnmt1 Overexpression Causes Genomic Hypermethylation, Loss of Imprinting, and Embryonic Lethality

Biallelic expression of Igf2 is frequently seen in cancers because Igf2 functions as a survival factor. In many tumors the activation of Igf2 expression has been correlated with de novo methylation of the imprinted region. We have compared the intrinsic susceptibilities of the imprinted region of Ig...

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Detaylı Bibliyografya
Asıl Yazarlar: Biniszkiewicz, Detlev, Gribnau, Joost, Ramsahoye, Bernard, Gaudet, François, Eggan, Kevin, Humpherys, David, Mastrangelo, Mary-Ann, Jun, Zhan, Walter, Jörn, Jaenisch, Rudolf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC133685/
https://ncbi.nlm.nih.gov/pubmed/11884600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2124-2135.2002
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