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Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins

Methylation at the DNA sequence 5′-CpG is required for mouse development. MeCP2 and MBD1 (formerly PCM1) are two known proteins that bind specifically to methylated DNA via a related amino acid motif and that can repress transcription. We describe here three novel human and mouse proteins (MBD2, MBD...

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Bibliografiske detaljer
Main Authors: Hendrich, Brian, Bird, Adrian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109239/
https://ncbi.nlm.nih.gov/pubmed/9774669
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