Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins

Methylation at the DNA sequence 5′-CpG is required for mouse development. MeCP2 and MBD1 (formerly PCM1) are two known proteins that bind specifically to methylated DNA via a related amino acid motif and that can repress transcription. We describe here three novel human and mouse proteins (MBD2, MBD...

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Publicado no:	Mol Cell Biol
Principais autores:	Hendrich, Brian, Bird, Adrian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109239/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6538
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