Dnmt1 Overexpression Causes Genomic Hypermethylation, Loss of Imprinting, and Embryonic Lethality
Biallelic expression of Igf2 is frequently seen in cancers because Igf2 functions as a survival factor. In many tumors the activation of Igf2 expression has been correlated with de novo methylation of the imprinted region. We have compared the intrinsic susceptibilities of the imprinted region of Ig...
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| Gepubliceerd in: | Mol Cell Biol |
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| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2002
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.7.2124-2135.2002 |
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