Programmable RNA tracking in Live Cells with CRISPR/Cas9

RNA-programmed genome editing using CRISPR/Cas9 from Streptococcus pyogenes has enabled rapid and accessible alteration of specific genomic loci in many organisms. A flexible means to target RNA would allow alteration and imaging of endogenous RNA transcripts analogous to CRISPR/Cas-based genomic to...

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Publicado en:Cell
Main Authors: Nelles, David A., Fang, Mark Y., O’Connell, Mitchell R., Xu, Jia L., Markmiller, Sebastian J., Doudna, Jennifer A., Yeo, Gene W.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826288/
https://ncbi.nlm.nih.gov/pubmed/26997482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.054
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