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Trouble in transitioning: activation of zygotic transcription can lead to DNA breakage and genome instability
Recent work from our laboratory has identified zygotic genome activation as a source of intrinsic DNA damage during germline development in C. elegans. More specifically, we have found that the primordial germ cells Z2 and Z3 experience DNA damage and damage checkpoint activation shortly after RNA p...
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| Publicat a: | Worm |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826147/ https://ncbi.nlm.nih.gov/pubmed/27123372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21624054.2015.1115946 |
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