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Chromosome-breakage genomic instability and chromothripsis in breast cancer

BACKGROUND: Chromosomal breakage followed by faulty DNA repair leads to gene amplifications and deletions in cancers. However, the mere assessment of the extent of genomic changes, amplifications and deletions may reduce the complexity of genomic data observed by array comparative genomic hybridizat...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Przybytkowski, Ewa, Lenkiewicz, Elizabeth, Barrett, Michael T, Klein, Kathleen, Nabavi, Sheida, Greenwood, Celia MT, Basik, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227294/
https://ncbi.nlm.nih.gov/pubmed/25011954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-579
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