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Chromosome-breakage genomic instability and chromothripsis in breast cancer

BACKGROUND: Chromosomal breakage followed by faulty DNA repair leads to gene amplifications and deletions in cancers. However, the mere assessment of the extent of genomic changes, amplifications and deletions may reduce the complexity of genomic data observed by array comparative genomic hybridizat...

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Dettagli Bibliografici
Pubblicato in:BMC Genomics
Autori principali: Przybytkowski, Ewa, Lenkiewicz, Elizabeth, Barrett, Michael T, Klein, Kathleen, Nabavi, Sheida, Greenwood, Celia MT, Basik, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227294/
https://ncbi.nlm.nih.gov/pubmed/25011954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-579
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